[Unpublished]

Can Sugary Drinks Really Cause Oral Cancer? 

Sugar-sweetened beverages (SSBs)—think sodas, fruit punches, and energy drinks—have long been tied to health issues like diabetes and obesity. But new research is shining a light on a more surprising connection: a significantly increased risk of oral cavity cancer (OCC), especially among women.

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May 12, 2025Informational
Can Sugary Drinks Really Cause Oral Cancer? 

Can Sugary Drinks Really Cause Oral Cancer? 

Sugar-sweetened beverages (SSBs)—think sodas, fruit punches, and energy drinks—have long been tied to health issues like diabetes and obesity. But new research is shining a light on a more surprising connection: a significantly increased risk of oral cavity cancer (OCC), especially among women.

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A Startling New Finding

A recent study by found that people who drink at least one sugar-sweetened beverage per day are nearly 5.46 times more likely to develop oral cavity cancer compared to those who rarely consume such drinks. What’s especially alarming is that the increased risk was present even among nonsmokers and nondrinkers—two groups typically considered low risk for this type of cancer.

This suggests that sugary drinks may be an independent and previously underestimated contributor to OCC.

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How Can Sugary Beverages Lead to Cancer?

Researchers suspect several biological mechanisms may be at play:

  • Inflammation: Excess sugar can cause chronic inflammation in the body, a condition that’s been linked to numerous cancers.

  • Microbiome Disruption: Sugary drinks may alter the balance of bacteria in the mouth, creating an environment more conducive to cancer development.

  • Acidity and Cell Damage: Many SSBs are highly acidic, which can erode protective tissue in the mouth and make cells more susceptible to damage and mutation.

Combined, these factors may lay the groundwork for cancerous cells to take hold.

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Not Just a Smoker’s Disease Anymore

Oral cavity cancer has traditionally been associated with smoking and heavy alcohol use. But researchers are now observing a steady increase in OCC among women who don’t engage in these behaviors. This new study offers an important clue: diet—particularly sugary beverage intake—might be a key risk factor.

With more women turning to sodas, sweet teas, and flavored waters as daily staples, it's possible that this shift in dietary habits is contributing to the trend.

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What You Can Do to Lower Your Risk

The good news? This is a risk factor you can control.

  • Cut back on sugary beverages or replace them with water, unsweetened tea, or sparkling water with no added sugar.

  • Read labels: Even “natural” fruit drinks can contain large amounts of added sugars.

  • Limit frequency: Even one sugary drink per week was associated with increased risk, so occasional consumption should be approached with caution.

By making simple changes, you may significantly reduce your risk—not just for OCC, but for a range of other chronic diseases.

Final Thoughts

This research is still emerging, but it serves as a powerful reminder that everyday choices—like what we drink—can have long-term consequences. While more studies are needed to confirm the connection, the evidence so far is compelling enough to reconsider reaching for that next soda.

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